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PhyloTree.org -
mtDNA tree Build 17 (18 Feb 2016): subtree L4 |
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Citation: van Oven M, Kayser M.
2009. Updated comprehensive phylogenetic tree of global human mitochondrial
DNA variation. Hum Mutat 30(2):E386-E394. |
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Nucleotide position numbers are consistent
with both the rCRS and the RSRS reference sequences. |
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Mutations are given in forward evolutionary
time direction in the format [ancestral base][position number][derived base],
e.g. "G15043A". |
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In case of a transversion, the derived allele
is shown in lowercase instead of uppercase, e.g. "C5178a". |
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Insertions are indicated by the position
number preceding the insertion followed by a dot (.), the relative insert
position, and the inserted base(s), e.g. "2156.1A". |
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Deletions are indicated by the letter
"d" following the (range of) position number(s) involved, e.g.
"A249d" or "8281-8289d". |
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Mutations that are reversions to an ancestral
state (back mutations) are indicated with an exclamation mark (!), two
exclamation marks for a double back mutation (!!), etc., e.g.
"A15301G!". |
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Coding-region mutations (np 577-16023) are
shown in black; control-region mutations (np 16024-576) in blue. |
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Mutations between brackets () are
recurrent/unstable within the respective clade, or are yet uncertain based on
current data. |
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Mutation motifs in italic are preliminary and are likely to be further refined as
additional sequences become available. |
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The mutations 309.1C(C), 315.1C, AC indels at
515-522, A16182c, A16183c, 16193.1C(C) and C16519T/T16519C were not
considered for phylogenetic reconstruction and are therefore excluded from
the tree. |
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Accession numbers provided at the tips of
branches are representative examples of mtDNA sequences available at GenBank
or from individuals included in HapMap/1000Genomes. |
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It may be convenient to use the Find function
(Ctrl+F) of your browser to search for a particular mutation or haplogroup. |
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Example accessions |
mt-MRCA (RSRS) |
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L1'2'3'4'5'6 |
C146T
C182T
T4312C T10664C C10915T
A11914G G13276A G16230A |
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L2'3'4'5'6 |
C152T A2758G
C2885T G7146A T8468C |
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L2'3'4'6 |
C195T
A247G
A825t T8655C A10688G
C10810T G13105A T13506C
G15301A A16129G
T16187C C16189T |
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L3'4'6 |
G4104A
A7521G |
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L3'4 |
T182C! T3594C
T7256C T13650C T16278C |
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L3 |
A769G
A1018G C16311T |
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N |
G8701A
C9540T G10398A C10873T
A15301G! |
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R |
T12705C
T16223C |
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R0 |
G73A A11719G |
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HV |
T14766C |
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H |
G2706A
T7028C |
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H2 |
G1438A |
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H2a |
G4769A |
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H2a2 |
G750A |
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H2a2a |
G8860A
G15326A |
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H2a2a1 |
G263A |
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rCRS |
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L4 |
T195C! G5460A
T16362C |
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L4a |
C198T G3357A
G10373A T11253C A11344G
T11485C T12414C T13174C
T14302C C16260T |
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L4a1 |
C325T T6167C
C7376T G7775A A11653G
T14000a A16207t |
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FJ460531 |
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L4a1a |
(C150T) G7762A
T8473C A8631G |
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DQ341064 |
EU092748 |
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L4a2 |
A12361G
C16264T |
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EU092935 |
EU092799 |
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L4b |
G709A
G3918A |
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L4b1 |
C150T
C195T!! T204C T4977C C10813T |
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NA19383 |
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L4b1a |
T199C
G513A
A1804G G3010A A3505G
C4017T C4029a T4216C
T4232C T7624C T8614C
C8974g C9248T G9986A
A12661t A13497G G14016A
G14905A C16179T
T16189C! C16239T C16320T |
JQ044811 |
EU092808 |
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L4b2 |
T146C!
A244G
A5460G! G6260A T8104C
A9855G T12609C A13470G
A16293t C16355T
A16399G |
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L4b2a |
A709G!
T1413C |
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L4b2a1 |
T152C!
T471C A547G G5471A T5580C
G5746A A6260G! G16274A |
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EU092942 |
DQ341065 |
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L4b2a2 |
C195T!! T1694C
A4949G A10783c T16172C |
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EF184627 |
EU092750 |
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L4b2a2a |
T2483C
T6620C T11137C |
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EU092938 |
EU092743 |
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L4b2a2b |
T6956C
G8485A T15970C C16287T |
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EU092951 |
EU092780 |
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L4b2a2c |
T391C C8478T
T15454C |
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NA19445 |
NA19435 |
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L4b2b |
A5128G
G7805A T10265C T12438C |
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NA19259 |
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L4b2b1 |
C340T A2220t
A4206G A16316G |
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JQ702504 |
NA19187 |
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